In this practical course the students learn different modern methods and special work techniques of analytical chemistry and their applications. They can estimate and evaluate the advantages and disadvantages of these methods critically. They learn how to present their work in a written report.

Main objectives of the lecture

The students should learn how to successfully work on an analytical problem: From sampling and sample preparation to analysis and data evaluation. 

They will learn new analytical techniques such as comprehensive two-dimensional chromatography, ion mobility mass spectrometry, ambient desorption ion sources etc.

Topics of the lecture

  • Repetition: Chromatography, HPLC, GC, CE and MS
  • DNA adduct analysis
  • DNA methylation
  • Analysis of active substances in Chinese herbal medicine or other natural products
  • Use of APLI for non-aromatic compounds
  • Analysis of surfactants in cleaners
  • Analysis of Phloem sap
  • Quantitative analysis with MALDI
  • Analysis of liquid inclusions in quartz samples
  • Analysis of isobaric compounds with MS


Wesentliche Ziele der Veranstaltung

  • Die Studierenden sollen erlernen wie ein analytisches Messergebnis korrekt angegeben wird.
  • Die Studierenden sollen modernste analytische Methoden erlernen und die Theorie dahinter verstehen.
  • Die Studierenden sollen erlernen, welche analytischen Methoden für welche analytischen 
    Fragestellungen geeignet sind und wo die Grenzen der Methoden liegen.


Themen der Veranstaltung

  • Statistik
  • Stationäre Phasen
  • Zweidimensionale Flüssigchromatographie
  • Überkritische Fluidchromatographie
  • Comprehensive zweidimensionale Gaschromatographie
  • Kapillarelektrophorese
  • AAS, ICP-OES und ICP-MS
  • Ionenquellen bei Atmosphärendruck für die Massenspektrometrie
  • Massenanalysatoren
  • Ionenmobilitäts-Massenspektrometrie
  • Bioanalytik

In this course quality programs and quality initiatives applied in quality management will be explained. Additionally, essential aspects of quality assurance in analytical chemistry are presented. 

Major aims of the course:

·       Overview of routine and state-of-the-art oxidative processes used in water and wastewater treatment

·       Advanced understanding of fundamental transformation processes involved in technical processes

·       Evaluation of advantages and drawbacks of oxidative processes for exemplary applications

·        Development of criteria for the selection of appropriate technological solutions

Part of the course tutorials will also be an introduction to reviewing scientific publications that students will practise on and present in the second half of the term.